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October 24, 2023
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January 14, 2025
Published
January 14, 2025
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Abstract

Antibiotic residues in food products can cause significant public health problems. Using antibiotics in livestock farming can potentially cause antibiotic residues in animal-based foods. We conducted this study to determine the results of chloramphenicol residue testing in processed honey, shrimp, and fish food products in the Sulawesi and Maluku regions. This study can determine the distribution of test results based on business type. This study is expected to produce recommendations to stakeholders to minimize the use of chloramphenicol, which is not covered by the provisions. The research samples came from processed honey, shrimp, and fish food products distributed in the Central Sulawesi, Ambon, Sofifi, Mamuju, Morotai, and Tanimbar regions in 2021-2022. Testing was carried out at the laboratory of the Indonesian Food and Drug Authority Regional Office in Palu according to the analysis method of PPPOMN 071/PA/17 concerning the Determination of Chloramphenicol Residue Levels in Shrimp by ELISA and MA PPPOMN 11/PA/09 concerning the Determination of Chloramphenicol Residue Levels in Honey by ELISA. Based on the test results, processed honey, shrimp, and fish food products were found to contain chloramphenicol residues. Of the total 92 samples tested, there were 15 honey products, four processed shrimp food products, and seven processed fish food products that did not meet the requirements (TMS). Chloramphenicol residue levels ranged from 0.01 to 0.09 ppb. The number of TMS samples in honey and fish food products with PIRT distribution permits was more significant in percentage when compared to products with MD/ML distribution permits. The rate of TMS in honey and processed fish food products with PIRT distribution permits was 53% and 21%, respectively. Further research on the source of chloramphenicol residues and the origin of honey, shrimp, and fish-producing areas needs to be conducted by relevant institutions or academics. In addition, it is necessary to conduct socialization and education among the public regarding the use of chloramphenicol antibiotics according to the provisions for both the treatment of diseases and livestock practices to minimize the presence of chloramphenicol residues in processed food products.

Keywords

antibiotic residue chloramphenicol honey processed fish processed shrimp residu antibiotik kloramfenikol madu olahan ikan olahan udang

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How to Cite
Ebtasari, M., & Aini , A. N. (2025). Study of Chloramphenicol Antibiotic Residues in Processed Food Products of Honey, Shrimp, and Fish in Sulawesi and Maluku. Eruditio : Indonesia Journal of Food and Drug Safety, 5(1), 1–9. https://doi.org/10.54384/eruditio.v5i1.157
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References

  1. Adi Saputra, S., & Arfi, F. (2021). Analisis Residu Kloramfenikol pada Udang Windu (Penaeus monodon) Menggunakan High Performance Liquid Cromatography (HPLC). Amina, 1(3), 126–131. https://doi.org/10.22373/amina.v1i3.489
  2. Al-Waili, N., Salom, K., Al-Ghamdi, A., & Ansari, M. J. (2012). Antibiotic, pesticide, and microbial contaminants of honey: Human health hazards. The Scientific World Journal, 2012, 1–9. https://doi.org/10.1100/2012/930849
  3. Aly, S. M., & Albutti, A. (2014). Antimicrobials use in aquaculture and their public health impact. Journal of Aquaculture Research and Development, 5(4). https://doi.org/10.4172/2155-9546.1000247
  4. BPOM. (2017). Peraturan Badan Pengawas OBat dan Makanan nomor 27 Tahun 2017 tentang pendaftaran Pangan Olahan. Badan Pengawas Obat dan Makanan.
  5. BPOM. (2018). Peraturan Badan Pengawas Obat dan Makanan Nomor 7 Tahun 2018 tentang Bahan Baku yang Dilarang dalam Pangan Olahan. Badan Pengawas Obat dan Makanan.
  6. BPOM. (2023). Pedoman Mitigasi Resiko Keberadaan Residu Antibiotik dan Mikrob Resisten Antibiotik pada Pangan Olahan. Badan Pengawas Obat dan Makanan.
  7. BSN. (2000). Batas Maksimum Cemaran Mikroba dan Batas Maksimum Residu dalam Bahan Makanan Asal Hewan. In Standar Nasional Indonesia (SNI 01-636). Badan Standar Nasional.
  8. Demirhan, B. E., & Demirhan, B. (2022). Detection of Antibiotic Residues in Blossom Honeys from Different Regions in Turkey by LC-MS/MS Method. Antibiotics, 11(3). https://doi.org/10.3390/antibiotics11030357
  9. Gowtham, P., Muthukumar, M., Rao, B. E., Kalpana, S., Keerthika, V., & JMA Dani Nishant, N. (2020). Impact of cooking methods of meat on antibiotic residues: Review. The Pharma Innovation, 9(12), 303–309. https://doi.org/10.22271/tpi.2020.v9.i12e.5454
  10. Kemenkes. (2012). Peraturan Menteri Kesehatan Republik Indonesia Nomor 033 Tahun 2012 Tentang Bahan Tambahan Pangan. Kementerian Kesehatan RI.
  11. Luo, L., Lu, S., Huang, C., Wang, F., Ren, Y., Cao, H., Lin, Q., Tan, Z., & Wen, X. (2021). A Survey of Chloramphenicol Residues in Aquatic Products of Shenzhen, South China. Food Additives & Contaminants: Part A, 38(6), 914–921. https://doi.org/10.1080/19440049.2021.1898680
  12. Menkem, Z. E., Ngangom, B. L., Tamunjoh, S. S. A., & Boyom, F. F. (2019). Antibiotic residues in food animals: Public health concern. Acta Ecologica Sinica, 39(5), 411–415. https://doi.org/10.1016/j.chnaes.2018.10.004
  13. Nisha, A. R. (2008). Antibiotic Residues - A Global Health Hazard. Veterinary World, 1(12), 375–377. http://dx.doi.org/10.5455/vetworld.2008.375-377
  14. Sari, J. M., & Hafiludin, H. (2023). Analisis Kadar Residu Antibiotik Kloramfenikol Pada Udang Vannamei (Litopenaeus Vannamei) Di Kabupaten Bangkalan Dengan Metode Elisa (Enzym Link Immunosorbent Assay). Juvenil:Jurnal Ilmiah Kelautan Dan Perikanan, 4(2), 84–89. https://doi.org/10.21107/juvenil.v4i2.18075
  15. Virgianti, S. E., Moelyaningrum, A. D., & Ningrum, P. T. (2022). Kandungan Residu Kloramfenikol Pada Udang Putih ( Litopenaeus vannamei ). Buletin Kesehatan Lingkungan Masyarakat, 41(4), 149–155. https://doi.org/10.31983/keslingmas.v41i4.9332
  16. Wang, Y., Zhang, W., Mhungu, F., Zhang, Y., Liu, Y., Li, Y., Luo, X., Pan, X., Huang, J., Zhong, X., Song, S., Li, H., Liu, Y., & Chen, K. (2021). Probabilistic Risk Assessment of Dietary Exposure to Chloramphenicol in Guangzhou, China. International Journal of Environmental Research and Public Health, 18(8805). https://doi.org/https://do.org/103390/ijerph/18168805
  17. Wibowo, A., Muliana, L., & Prabowo, M. H. (2010). Analisis Residu Antibiotik Kloramfenikol dalam Daging Ikan Gurami (Osphronemus gouramy, Lac( Menggunakan Metode High Performance Liquid Chromatography. Jurnal Ilmiah Farmasi, 7(1), 23–37.